【】Objective? To investigate the value of ultrasound measurement of fetal venous catheter hemodynamic parameters combined with serum placental growth factor (PLGF) in predicting pregnancy outcome of pregnancy-induced hypertension (PIH).Method? The clinical data of 80 patients diagnosed with pregnancy-induced hypertension after prenatal examination in our hospital from April 2022 to April 2023 were retrospectively analyzed, and they were set as case group, and 100 pregnant women with normal prenatal examination during the same period were selected as control group. The hemodynamic parameters (pulse index (PI), resistance index (RI), peak-to-valley ratio (S/D) of blood flow velocity, venous catheter flow rate), serum PLGF level and the incidence of adverse pregnancy outcomes were compared between the two groups. According to the pregnancy outcomes of pregnan-induced hypertension group, the two groups were divided into adverse outcome group (n=18) and good outcome group (n=62). Baseline data, fetal venous catheter hemodynamic parameters and PLGF levels of the two groups were compared, and the value of fetal venous catheter hemodynamic parameters and serum PLGF levels in predicting adverse pregnancy outcomes of pregnan-induced hypertension was analyzed by ROC. Multivariate Logistic regression was used to analyze the risk factors of pregnancy-induced hypertension.Result? The hemodynamic parameters of fetal venous catheter in case group were higher than those in control group, and the serum PLGF level was lower than that in control group (P < 0.05). The incidence of adverse pregnancy outcome in case group was higher than that in control group (P < 0.05). Prepregnancy body mass index (BMI) , PI, RI, S/D, venous catheter flow rate and the proportion of patients aged ≥35 years in the adverse outcome group were higher than those in the good outcome group (P < 0.05). ROC analysis confirmed that both fetal venous catheter hemodynamic parameters and serum PLGF level could be used to predict the adverse pregnancy outcome of pregnacy-induced hypertension, and the areas under the curve were 0.888, 0.717, 0.913, 0.911, 0.984, 0.709, respectively. The area under the curve of fetal venous catheter hemodynamic parameters combined with serum PLGF was 0.957 (P < 0.05). Multivariate Logistic regression analysis confirmed that age [OR=1.357 (95%CI: 1.033~1.783)], pre-pregnancy BMI[OR=1.536 (95%CI: 1.118~2.110)], PI[OR=1.797 (95%CI: 1.122~2.878)], RI[OR=1.751 (95%CI: 1.121~2.735)], S/D[OR=1.886 (95%CI: 1.075~3.309)], venous catheter flow rate [OR=1.967 (95%CI: 1.967) 1.142~3.388)] and PLGF[OR=2.132 (95%CI: 1.176~3.865)] are risk factors for pregnancy-induced hypertension (P < 0.05).Conclusion? Abnormally high expression of fetal venous catheter hemodynamic parameters and decreased serum PLGF level are closely related to the occurrence and development of pregnancy-induced hypertension. These indicators can effectively predict pregnancy outcome, and combined detection can obtain higher sensitivity and specificity.